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patient and donor","Disease status and organ function assessment (heart, lung, liver, kidney)","Infection screening and dental evaluation","Central venous catheter placement","Conditioning chemotherapy, with or without radiation, before infusion","Counseling on fertility preservation and informed consent"],"recovery_timeline":[{"phase":"Conditioning","description":"Chemotherapy with or without total body irradiation over several days before marrow infusion.","restrictions":["Inpatient isolation precautions"]},{"phase":"Infusion and neutropenia","description":"Donor marrow infused intravenously; blood counts fall then engraftment typically occurs after about 2–4 weeks, with supportive care and transfusions.","restrictions":["Protective isolation","Strict infection precautions"]},{"phase":"Early post-discharge","description":"Frequent outpatient visits, immunosuppression and monitoring for GVHD and infection over the first 3 months.","restrictions":["Avoid crowds and infection exposure","Diet and medication restrictions per team","Stay near transplant center"]},{"phase":"Long-term recovery","description":"Gradual immune recovery over months to a year or more; immunosuppression tapered if no GVHD.","restrictions":["Vaccination schedule re-started per team","Sun protection and ongoing surveillance"]}],"rehabilitation_days":{"min":90,"max":180,"unit":"days","qualifier":"Return to basic daily function; depends on conditioning intensity, GVHD and complications."},"result_longevity":"Successful engraftment gives lifelong donor-derived blood production. Disease cure depends on diagnosis and risk, with relapse most likely in the first two years.","revision_rate_pct":{"min":2,"max":10,"unit":"percent","qualifier":"Graft failure or rejection needing second transplant or donor cell boost; higher in non-malignant and high-risk disease."},"scars":"No surgical scars for the recipient, only a small mark from the central venous catheter. The donor has tiny puncture marks at the pelvic harvest sites.","sessions_or_stages":{"sessions":{"min":1,"max":1,"unit":"visits","qualifier":"One marrow infusion after conditioning; a second transplant is only for graft failure."},"stages":[{"code":"workup","label":"Donor and patient HLA typing and fitness evaluation","after":{"min":0,"max":30,"unit":"days","qualifier":"Days from first evaluation to admission; completed before conditioning."}},{"code":"conditioning","label":"Conditioning chemotherapy with or without radiation","after":{"min":0,"max":2,"unit":"days","qualifier":"Starts at admission; runs several days before infusion."}},{"code":"infusion","label":"Donor marrow harvest and intravenous infusion","after":{"min":7,"max":9,"unit":"days","qualifier":"Day zero, after conditioning; about 7–9 days after admission."}},{"code":"engraftment","label":"Neutropenia and engraftment monitoring","after":{"min":21,"max":37,"unit":"days","qualifier":"Counts recover about 2–4 weeks after infusion; counted from admission."}},{"code":"early_outpatient","label":"Outpatient GVHD and infection monitoring","after":{"min":30,"max":120,"unit":"days","qualifier":"Stay near center about 100 days."}}],"qualifier":"Single transplant, with conditioning beforehand and about 100 days of monitoring after."},"success":{"metric":"Overall survival after related-donor marrow transplant","value":55,"unit":"percent","horizon":"2 years","population":"Adults with leukemia or marrow failure, matched sibling donor, standard-risk","evidence_status":"limited"},"techniques":[{"name":"Myeloablative conditioning followed by related-donor marrow infusion","suits_whom":"Typically younger, fit patients with high-risk malignant or marrow failure disease.","recovery":"Longer neutropenia; inpatient stay of several weeks."},{"name":"Reduced-intensity conditioning followed by related-donor marrow infusion","suits_whom":"Older or less fit patients, or those with comorbidities.","recovery":"Less conditioning toxicity; still requires weeks of monitoring and GVHD vigilance."}],"treatment_conditions":["inpatient"],"treatment_duration_hours":{"min":1,"max":4,"unit":"hours","qualifier":"Marrow infusion takes hours; donor harvest takes about 1–2 hours; conditioning spans several days separately."},"initial_assessment_documents":["Bone marrow biopsy and pathology report","Cytogenetic and molecular mutation report","Recent complete blood count results","HLA typing of patient and sibling donors","Prior chemotherapy and transplant treatment summary","Heart, lung, liver and kidney test results"],"travel_trips":{"min":1,"max":3,"one_trip_possible":true,"qualifier":"Donor and patient travel together; one stay covers workup, transplant and about 100 days' monitoring. Some centers split follow-up."},"clinic_checks":{"status":"ok","items":[{"id":"C1","text":"Ask whether a doctor is always present in the clinic and whether a high dependency or intensive care unit exists","scope":"treatment_abroad","source":{"url":"https://www.bapras.org.uk/public/patient-information/cosmetic-surgery/cosmetic-surgery-abroad","host":"bapras.org.uk","quote":"Is there always a doctor in the clinic and is there a high dependency or intensive care unit?","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C2","text":"Ask whether the surgeon and the facility use a surgical safety checklist, which can reduce complications","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Do the surgeon and his/her facility use a safety checklist?","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C3","text":"Decide 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