Pagina 4 - I migliori medici di Ablazione con ultrasuoni focalizzati ad alta intensità (HIFU) - TOP-109medici

Dr. Mehmet Tonge is a neurosurgeon with expertise in Stereotactic and Functional Neurosurgery. He specializes in MR Guided Focused Ultrasound, deep brain stimulation, Gamma Knife Radiosurgery, and surgery for movement disorders, pain, and spasticity.

Dr. Tonge has published 32 articles in international and national journals and written 12 book chapters. He has presented 92 oral and poster presentations and delivered 41 invited lectures. He completed a Deep Brain Stimulation Fellowship at Maastricht University and finished the 4-year EANS training cycle. Dr. Tonge is known for his research and clinical work in functional neurosurgery.

Dr. George Tie is an expert in minimally invasive urological surgery. He manages kidney stones and performs advanced prostate procedures, including TURP and laser surgery. He also treats urologic cancers using laparoscopic, endoscopic, and robotic techniques.

Dr. Tie is known for his high success rates and precise surgical skills. He focuses on patient comfort and fast recovery. He provides evidence-based care to international patients in a modern setting, ensuring advanced and reliable urological treatment.

Prof. Ramazan Gökhan ATIŞ, M.D.

Languages: English

Urology

Areas of Expertise and Interest

• Paediatric Urology
• Robotic Surgery
• Endourology
• Genitourinary Reconstructive Surgery
• Urological Oncology
• Urological Neurology
   

Education

• Cağaloğlu Anatolian High School, Istanbul – Graduated in 1996
• Istanbul University, Istanbul Faculty of Medicine (Çapa) – M.D., 2002
• Urology Residency, Istanbul Şişli Etfal Training and Research Hospital – 2002–2008
• Laparoscopy and Robotic Urology Training, Heidelberg University, Heilbronn Clinic – 2011

Career

• Urology Specialist, Istanbul Göztepe Training and Research Hospital – 2009–2014
• Associate Professor Title Achieved – September 2014
• Executive Board Member, Endourology Society – Since 2017
• Member, European Association of Urology – Young Academic Urologists (EAU-YAU), Endourology Working Group – 2018–2020
• Professor of Urology, Istanbul Medeniyet University – Appointed in January 2021
• Urologist, Şişli Memorial Hospital – Since August 1, 2022
   

Born in 1978 in Istanbul, Prof. Dr. Ramazan Gökhan ATIŞ completed his medical degree at Istanbul University’s Faculty of Medicine in 2002. He pursued his urology specialization at Şişli Etfal Training and Research Hospital and became a certified urologist in February 2008. Following his military service at Edremit Military Hospital, he began working at Göztepe Training and Research Hospital in 2009.

In 2011, he received training in laparoscopic and robotic urology at Heidelberg University’s Heilbronn Clinic. Between 2009 and 2014, he conducted numerous scientific studies, especially in the field of endourology, earning the title of Associate Professor in 2014.

Since 2017, he has served on the board of the Endourology Society. In 2018, he was selected to the European Association of Urology’s Young Academic Urologists (EAU-YAU) Endourology Working Group, actively serving for two years. In January 2021, he was appointed as a Professor at Istanbul Medeniyet University. Since August 1, 2022, he has continued his clinical practice, initially at Şişli Memorial Hospital and currently at Medipol Acıbadem District Hospital.

Dr. Auala Hubert is a board-certified medical oncologist and radiotherapist with 33 years of clinical experience. She works at Hadassah Medical Center and speaks both English and Hebrew. Dr. Hubert leads the Gastrointestinal Cancer Center. She is also a senior physician in the Oncology Department.

She earned her M.D. from Hadassah University Hospital. She holds board certifications in oncology and radiotherapy. Dr. Hubert has passed USMLE Parts I and II. She is a member of the Israel Society of Clinical Oncology, Israel Medical Society, and Israel Cancer Association. Dr. Hubert also serves on several medical and social service committees, where she helps advance cancer care.

Dr. Lan Kerdpol is an Obstetrics and Gynecology (OB-GYN) specialist with 29 years of clinical experience. Dr. Kerdpol practices at Navamin9 Hospital in Bangkok, Thailand. Languages: English and Thai.

Education: Doctor of Medicine (M.D.), Faculty of Medicine, Mahidol University.

Accreditation: Diploma of the Thai Board of Obstetrics and Gynecology, Thai Medical Council.

Dr. Halil Can is a Professor of Neurosurgery (2025; Associate Professor 2020). He completed neurosurgical training at Istanbul University–Istanbul Faculty of Medicine in 2007. His clinical focus includes endoscopic and microsurgical spine surgery for fractures, tumors, and degenerative disease; advanced pain procedures; endoscopic skull base and pituitary surgery; and neurovascular, neuro-oncologic, and peripheral nerve surgery.

He has 21 international peer-reviewed papers (SCI/SSCI). Topics include cadaveric morphometry of Kambin’s triangle and the transforaminal triangular working zone, lumbar arterial and anterior approach anatomy, and an in vitro test of a new lumbar fixation device.

His clinical studies include a single-team series of 81 posterior circulation aneurysms, with 13 flow-diversion cases. He also reported five spinal cavernous malformation cases. He conducted Phase I safety and feasibility stem-cell trials in pediatric hypoxic-ischemic encephalopathy and in chronic complete spinal cord injury.

Dr. Meryem Eken is an obstetrician-gynecologist and IVF specialist. She earned her M.D. and completed her residency at Istanbul University. She completed IVF clinical training at Zeynep Kamil in 2017. She led the IVF Unit at Hisar Intercontinental Hospital from 2020 to 2025. She heads the IVF Unit at Bahçeşehir University Medical Park Göztepe Hospital. She started in 2025. She has served on the faculty of Üsküdar University since 2024. She became a professor at Biruni University in 2025.

Her clinical focus includes infertility, intrauterine insemination (IUI), natural-cycle IVF, hysteroscopy, endometriosis, and minimally invasive myomectomy. She has authored or co-authored more than 30 peer-reviewed international articles. Several appeared in SCI and SSCI journals. In 2016, she received First Prize for an oral presentation from the Turkish Society of Gynecology and Obstetrics.

Dr. Ali Osman Mucuoglu is a neurosurgeon. He completed his neurosurgery residency at Dokuz Eylül University from 2013 to 2019 after graduating from Eskişehir Osmangazi University in 2012 (2005–2012). He worked at Dokuz Eylül University and Muş State Hospital from 2019 to 2021. He has practiced at Atlas University Hospital since 2021.

He has five publications. These include a case report in the International Journal of Surgery Case Reports that has been cited seven times. He also reported on 3D printer‑assisted transsphenoidal hypophysectomy and on emergency minimally invasive intracerebral hemorrhage (ICH) surgery. He delivered an oral presentation at the 33rd Turkish Neurosurgical Society Congress in 2019.

He is a member of the Turkish Neurosurgical Society, the European Association of Neurosurgical Societies, and the Istanbul Chamber of Medicine. His advanced training includes spinal surgery courses in 2016 and 2017, the European Training Course on Head Injury and Functional Neurosurgery in 2017, and Surgical Neuroanatomy in 2017. He also holds an animal experimentation certificate from 2016.

Dr. Eduard Linecki is a neurologist at Hadassah Medical Center with more than 23 years of clinical experience. He focuses on neurology, polyneuropathy, and neurooncology. He has strong expertise in managing and treating Parkinson's disease.

Dr. Linecki earned his medical degree in 1996. He completed his internship at Hadassah in 2001. He is known for achieving good results in Parkinson's disease therapy. He is also skilled in treating complex nervous system disorders.

Experience

2019 - 2022 Medipol University

2010 Private Nisa Hospital

2008 - 2010 Kaman State Hospital

Education

2008

Istanbul University Cerrahpaşa Faculty of Medicine, Obstetrics and Gynecology

2002

Istanbul University, Istanbul Faculty of Medicine

Experience

2017 - 2022 Haseki Training and Research Hospital, Associate Professor

2017 - 2022 Haseki Training and Research Hospital

2013 - 2017 Haseki Training and Research Hospital

2013 - 2017 Haseki Training and Research Hospital, Chief Resident

2010 - 2013 Silivri State Hospital (Compulsory Service Obligation)

2008 - 2008 University of Michigan Medical School

2005 - 2010 Istanbul Medical Faculty, Department of Urology

Education

2010 Istanbul University, Istanbul Medical Faculty, Department of Urology

2004 Istanbul University, Istanbul Medical Faculty

Publications

International Peer-Reviewed Journals:

Culpan M, Atis G, Sanli O, Bozkurt Y, Atmaca AF, Semerci B, Kutsal C, Canda AE, Akbulut F, Tugcu V, Boylu U, Erturhan S, Koca O, Ateş F, Halis F, Soyupek S, Turna B, Cakmak S, Sahin S, Erdem S, Yildirim A. "Comparison of Tumor Enucleation and Standard Partial Nephrectomy According to Trifecta Outcomes: A Multicenter Study by the Turkish Academy of Urology, Uro-Oncology Working Group." J Invest Surg. 2022 May;35(5):1112-1118.

Sahan M, Sarilar O, Akbulut MF, Demir E, Savun M, Sen O, Ozgor F. "Flexible ureterorenoscopy and laser lithotripsy with regional anesthesia vs general anesthesia: A prospective randomized study." Int Braz J Urol. 2020 Nov-Dec;46(6):1010-1018.

Cubuk A, Yanaral F, Savun M, Ayranci A, Erbin A, Yazici O, Akbulut MF, Sarilar O. "Modified autologous transobturator tape surgery - evaluation of short-term results." Ginekol Pol. 2020;91(2):51-56.

Kandemir E, Savun M, Sezer A, Erbin A, Akbulut MF, Sarilar Ö. "Comparison of Miniaturized Percutaneous Nephrolithotomy and Standard Percutaneous Nephrolithotomy in Secondary Patients: A Randomized Prospective Study." J Endourol. 2020 Jan;34(1):26-32.

Ucpinar B, Erbin A, Ayranci A, Caglar U, Alis D, Basal S, Sarilar O, Akbulut MF. "Prediction of recurrence in non-muscle invasive bladder cancer patients. Do patient characteristics matter?" J BUON. 2019 Jul-Aug;24(4):1659-1665.

Ozdemir H, Erbin A, Sahan M, Savun M, Cubuk A, Yazici O, Akbulut MF, Sarilar O. "Comparison of supine and prone miniaturized percutaneous nephrolithotomy in the treatment of lower pole, middle pole and renal pelvic stones: A matched pair analysis." Int Braz J Urol. 2019 Sep-Oct;45(5):956-964.

Erbin A, Ucpinar B, Cubuk A, Yazici O, Uysal H, Savun M, Basal S, Akbulut MF. "The Impact of Sheath Size in Miniaturized Percutaneous Nephrolithotomy in Adult Patients; A Matched-pair Analysis." Urol J. 2019 Dec 24;16(6):536-540.

Güler A, Erbin A, Ucpinar B, Savun M, Sarilar O, Akbulut MF. "Comparison of miniaturized percutaneous nephrolithotomy and standard percutaneous nephrolithotomy for the treatment of large kidney stones: a randomized prospective study." Urolithiasis. 2019 Jun;47(3):289-295.

Yanaral F, Ozgor F, Savun M, Agbas A, Akbulut F, Sarilar O. "Shock-wave Lithotripsy for Pediatric Patients: Which Nomogram Can Better Predict Postoperative Outcomes?" Urology. 2018 Jul;117:126-130.

Arslan B, Akbulut MF, Onuk O, Küçüktopçu O, Çilesiz NC, Ozkan A, Yazıcı G. "A comparison of Amplatz dilators and metal dilators for tract dilatation in mini-percutaneous nephrolithotomy." Int Urol Nephrol. 2017 Apr;49(4):581-585.

Akbulut F, Kucuktopcu O, Kandemir E, Ucpinar B, Ozgor F, Simsek A, Arslan B, Erbin A, Yanaral F, Binbay M, Gurbuz G. "Efficacy and safety of mini percutaneous nephrolithotomy in obese patients." Springerplus. 2016 Jul 22;5(1):1148.

Sancak EB, Oguz S, Akbulut T, Uludag A, Akbas A, Kurt O, Akbulut MF. "Female sexual dysfunction in androgenetic alopecia: Case-control study." Can Urol Assoc J. 2016, July;10(7-8):E251-256.

Akbulut F, Kucuktopcu O, Kandemir E, Sonmezay E, Simsek A, Ozgor F, Binbay M, Muslumanoglu AY, Gurbuz G. "Comparison of flexible ureterorenoscopy and mini-percutaneous nephrolithotomy in treatment of lower calyceal stones smaller than 2 cm." Ren Fail. 2016;38(1):163-7.

Tok A, Akbulut F, Buldu I, Karatag T, Kucuktopcu O, Gurbuz G, Istanbulluoglu O, Armagan A, Tepeler A, Tasci AI. "Comparison of microperc and mini-percutaneous nephrolithotomy for medium-sized lower calyx stones." Urolithiasis. 2016 Apr;44(2):155-9.

Akbulut F, Tok A, Penbegul N, Daggulli M, Eryildirim B, Adanur S, Gurbuz G, Celik H, Utangac MM, Dede O, Bodakcı MN, Tepeler A, Sarica K. "Colon perforation related to percutaneous nephrolithotomy: from diagnosis to treatment." Urolithiasis. 2015 Nov;43(6):521-6.

Ozluk Y, Sari S, Guzel NT, Firat P, Akbulut F, Kilicaslan I. "Mixed epithelial and stromal tumor of the kidney with sarcomatous transformation metastatic to the lung: A case report." Anal Quant Cytopathol Histpathol. 2015 Jun;37(3):199-205.

Ozgor F, Kucuktopcu O, Sarilar O, Toptas M, Simsek A, Gurbuz ZG, Akbulut MF, Binbay M. "Does previous open renal surgery or percutaneous nephrolithotomy affect the outcomes and complications of percutaneous nephrolithotomy." Urolithiasis. 2015 Nov;43(6):541-7.

Ugurlu İM, Akman T, Binbay M, Tekinarslan E, Yazıcı Ö, Akbulut MF, Özgör F, Müslümanoğlu AY. "Outcomes of retrograde flexible ureteroscopy and laser lithotripsy for stone disease in patients with anomalous kidneys." Urolithiasis. 2015 Feb;43(1):77-82.

Simsek A, Ozgor F, Kirecci SL, Akbulut MF, Sonmezay E, Yuksel B, Kucuktopcu O, Gurbuz ZG. "Results of tension-free vaginal tape for recurrent stress urinary incontinence after unsuccessful transobturator tape surgery." J Obstet Gynaecol Res. 2014 Jun;40(6):1764-9.

Simsek A, Kirecci SL, Kucuktopcu O, Ozgor F, Akbulut MF, Sarilar O, Ozkuvanci U, Gurbuz ZG. "Comparison of paroxetine and dapoxetine, a novel selective serotonin reuptake inhibitor in the treatment of premature ejaculation." Asian J Androl. 2014 Sep-Oct;16(5):725-7.

Akbulut F, Kucuktopcu O, Sonmezay E, Simsek A, Ozgor F, Gurbuz ZG. "Partial penectomy after debridement of a Fournier's gangrene progressing with an isolated penile necrosis." Ulus Travma Acil Cerrahi Derg. 2014 Sep;20(5):385-8.

Simsek A, Ozgor F, Yuksel B, Kucuktopcu O, Kirecci SL, Toptas M, Sarilar O, Berberoglu AY, Gurbuz ZG, Mimaroglu S, Akbulut F, Baykal M, Arslan B, Savun M, Ucpinar B. "Female sexual function after transobturator tape in women with urodynamic stress urinary incontinence." Springerplus. 2014 Sep 30;3:570.

Akbulut F, Akman T, Salabas E, Dincer M, Ortac M, Kadioglu A. "Neurovascular bundle dissection for Nesbit procedure in congenital penile curvature patients: medial or lateral?" Asian J Androl. 2014 May-Jun;16(3):442-5.

Kadioglu A, Sanli O, Akman T, Canguven O, Aydin M, Akbulut F, Kucukdurmaz F. "Factors Affecting the Degree of Penile Deformity in Peyronie's Disease: An Analysis of 1001 Patients." J Androl. 2011 Sep-Oct;32(5):502-8.

Akman T, Sanli O, Uluocak N, Akbulut F, Nane I, Demir S, Kadioglu A. "The most commonly altered type of Peyronie's disease deformity under oral colchicine treatment is lateral curvature that mostly shifts to the dorsal side." Andrologia. 2011 Feb;43(1):28-33.

Akbulut MF, Sanli O, Kadioglu A. "Editorial Comment on: Are Infertile Men Less Healthy than Fertile Men? Results of a Prospective Case-Control Survey." Eur Urol. 2009 Dec;56(6):1032.

Acar O, Akinci M, Uluocak N, Akbulut F, Kilicaslan I, Gokce O. "Paratesticular metastasis of malignant melanoma: a case report." Kaohsiung J Med Sci. 2008 Jun;24(6):315-8.

Çubuk A, Erbin A, Savun M, Ayranci A, Üçpınar B, Yanaral F, Sarılar Ö, Basal Ş, Akbulut MF. "Autologous transobturator midurethral sling." Turk J Urol. 2018 Dec 21;45(3):230-232.

Sarılar Ö, Özgör F, Küçüktopçu O, Uçpınar B, Akbulut MF, Savun M, Gürbüz ZG, Binbay M. "Is standard percutaneous nephrolithotomy still the standard treatment modality for renal stones less than three centimeters?" Turk J Urol. 2017 Jun;43(2):165-170.

Akbulut F, Savun M, Ucpinar B, Sahan M, Arslan B, Ozgor F, Simsek A, Berberoglu AY, Baykal M, Binbay M. "Duplicated Renal System with H Shaped Ureter: An Extraordinary Anomaly." Case Rep Urol. 2016;2016:4062515.

Akbulut F, Kucuktopcu O, Kandemir E, Sonmezay E, Simsek A, Ucpinar B, Ozgor F, Gurbuz G. "Comparison of efficacy of laser lithotripter with ultrasonic lithotripter in mini percutaneous nephrolithotomy." Arch Ital Urol Androl. 2016 Jan 14;87(4):276-9.

Ozgor F, Simsek A, Aydogdu O, Kucuktopcu O, Sarilar O, Berberoglu AY, Akbulut MF, Binbay M. "Bleeding during laparoscopic partial nephrectomy: Can a hemostatic matrix help to improve hemostasis?"

Specializations

Brain Tumors

Aneurysm Surgery

Pituitary Surgery

Spine Surgery

Waist neck and back hernias

Spine Tumors

Spinal Fractures

Peripheral Nerve Surgery

Specializations

Prostate Diseases Treatment

Kidney, Urinary Tract, Bladder Stone and Tumor Treatment

Infertility, Treatment of Sexual Diseases

Urinary Incontinence Treatment

Circumcision, Undescended Testicle Treatment

Specializations

RIRS (Laser Stone Breaking in the Kidney)

Open-Closed Prostate Surgeries

Urological Cancer Surgeries

Urinary Incontinence Treatment

Infertility Treatment

Dr. Siriporn Cheawchanwej is an aesthetic and anti-aging physician. She holds a Diploma in Aesthetic Medicine from the American Academy of Aesthetic Medicine and completed advanced training at the School of Anti-Aging and Regenerative Medicine and in Facial Design at Mae Fah Luang University.

Her international training includes Restylane seminars in Sweden (2006–2008) and the International Symposium of Botulinum Toxin in Korea. She also attended the Asia Pacific Rhinoplasty Expert Forum in Seoul, the International Congress of Minimal Invasive Plastic Surgery & Dermatology in Seoul, and IMCAS Asia 2009.

Il Dott. Teanchai Siricharoensang porta 13 anni di esperienza in urologia dal Samitivej Hospital di Bangkok, specializzandosi in procedure laparoscopiche ed endoscopiche avanzate.

• Chirurgo laparoscopico avanzato con ampia formazione
• Specialista certificato in lipolisi ultrasonica
• Membro dell'American Urological Association
• Certificazione di specialista in anti-invecchiamento

Bойко Сергій Олександрович — urologo, oncochirurgo, professore presso UzhNU, con 26 anni di esperienza. Ha completato la sua formazione all'Università Statale di Užgorod (1996), ha ottenuto il certificato di urologo presso LNMU intitolata a Danilo Halytsky (1998), ha difeso la sua tesi di dottorato in urologia presso l'Istituto di Urologia dell'Accademia delle Scienze Mediche dell'Ucraina (2000), ed è stato attestato come docente (2004). Possiede certificati nelle specialità di «Diagnostica ecografica» (2010) e «Chirurgia» (2015), con categorie superiori in urologia (2019), chirurgia (2020) e ecografia (2021). Nel 2020 ha conseguito il dottorato in Scienze Mediche nella specialità «Chirurgia» e nel 2022 la specializzazione in oncochirurgia (NUOZ Ucraina intitolata a P.L. Šupika). Dal 2021 è professore presso il dipartimento di malattie chirurgiche di UzhNU.

Interessi professionali: urologia endoscopica, aperta e ricostruttiva e oncourologia (TUR prostata/vescica, biopsie, nefrectomia/resezione renale, cistectomia/cistoprostatectomia, prostatectomia radicale, surrenalectomia, dissezioni linfonodali, operazioni di Bricker/Studer, plastica del segmento pielo-ureterale, urologia d'urgenza). Consulenza e trattamento di malattie infiammatorie del sistema genitourinario, urolitiasi, IPB, patologie oncologiche dei reni, delle vie urinarie e degli organi genitali maschili, esecuzione di interventi ricostruttivi ed estetici negli uomini.

Appartenenze: ESMO, ESOU, Associazione degli urologi dell'Ucraina, Associazione degli oncourologi dell'Ucraina, associazioni regionali degli urologi e chirurghi. Partecipa regolarmente a corsi di aggiornamento professionale e a forum nazionali e internazionali.

Areas Of Interest 

Laser Prostate Surgery (HoLEP, ThuFLEP) 

Robotic and Laparoscopic Urological Surgery 

Robotic MR/ Ultrasound Prostate Fusion Biopsy 

Urological Oncologic Surgery 

Andrology 

Benign Prostatic Hyperplasia (water vapor to the prostate) 

Focal Treatment for Prostate Cancer (HIFU, Nano Knife) 

Education 

Elementary school- Kolak, Denizli, Turkey (1986 - 1990) 

Secondary School- Yenimahalle School, Yatagan, Turkey (1990 - 1994) 

High School- Turgutreis High School, Muğla, Turkey (1994 - 1998) 

Gülhane Military Medical Academy Faculty of Medicine, Ankara, Turkey (1998 - 2004) 

Gülhane Military Medical Academy Urology Clinic Specialty Training, Ankara, Turkey (2007 - 2012)

Experience 

Liv Ulus Hospital 

Şişli Kolan International Hospital 

Istanbul University of Health and Technology 

Gülhane Military Medical Academy (GATA) 

Gülhane Education and Research Hospital 

University of Health Sciences, Gülhane Faculty of Medicine

Memberships

Turkish Urological Association 

Society of Endourology 

European Society of Urology (EAU) 

American Urological Association (AUA) 

World Society of Endourology

Education

Undergraduate: Faculty of Medicine, Gazi University, 2004-2010
Internship Abroad: Erasmus University Erasmus Medical Center, Rotterdam, 2007
Residency in Medicine: Department of Obstetrics and Gynecology, Gazi University, 2011-2016
Minor Specialization: Gynecologic Oncology Surgery, Erciyes University, 2018-2021
Advanced Cancer Surgery Training: Charité - Universitätsmedizin Berlin, 2019-2020
Ph: Molecular Oncology, University of Health Sciences, 2023-present

Experience

Associate Professor Doctor: Tekirdag Dr. Ismail Fehmi Cumalioglu City Hospital, Gynecologic Oncology Surgery Clinic, 2024-present
Gynecologic Oncology Surgery Specialist: Tekirdag Dr. İsmail Fehmi Cumalıoğlu City Hospital, 2021-2024
Gynecology and Obstetrics Specialist: Sarıkamış State Hospital, 2017-2018
Gynecology and Obstetrics Specialist: Ankara Keçiören Occupational Diseases Hospital, 2016-2017.

Medical Interests

• Advanced gynaecological cancer surgery
• Minimally invasive laparoscopic gynaecological surgeries
• Minimally invasive laparoscopic gynaecological cancer surgery
• Robotic surgeries
• Deep infiltrative endometriosis surgery
• Patient education, rehabilitation-prehabilitation before and after surgery in cancer patients
• Planning preventive treatments for lymphoedema in cancer patients
• ERAS (Enhanced Recovery after Surgery)- Rapid recovery after surgery
• HPV diagnosis and treatment methods
• Colposcopy
• Use of molecular oncology and tumour immunology principles in surgical practice
• Use of artificial intelligence in gynaecological cancers
• Improving international communication between colleagues in gynaecological oncology
• Surgical management of high-risk pregnancies with placental adhesion anomaly/placenta accreta spectrum