Sheba Pediatric CAR-T Program for Primary CNS Lymphoma at JCI accredited and Top-10 Hospitals 2026 by Newsweek Hospital
Cosa include questo pacchetto
Procedure mediche
- Consulto con un ematologo
- Analisi estesa del sangue
- Diagnostica oncologica complessa
- Biopsia del linfonodo sentinella
- Consulto con un oncoematologo
- Diagnosi completa dei linfomi
- PET/CT nel linfoma
- Esame del sangue per linfoma
- Terapia con cellule CAR-T
- 3 pasti al giorno dal nutrizionista
- Servizi infermieristici 24 ore su 24
- Elettrocardiogramma (ECG)
- Esami del sangue
- Radiografia del torace
- Test anti-HIV
- Test Anti-HBC
- Test Anti-HCVAb
- Ecocardiografia
- Emocromo completo (CBC)
- Esame di biochimica del sangue
- PET/TC
- Consultazione con un oncologo
- Consultazione con un ematologo
- Consultazione con un immunologo
- Consultazione con un cardiologo
- Consultazione con un ematologo pediatrico
- Consultazione con un pediatra
- Consultazione con un oncoematologo
- Risonanza magnetica della testa
- Biopsia
- Emocromo completo con marcatori tumorali e proteinogramma
Durata
- 21 giorni in ospedale
Alloggio
Ospedalizzazione
Trasporto
Trasferimento aeroporto-clinica-aeroporto
Informazioni aggiuntive
Sheba Pediatric CAR-T Program for Primary CNS Lymphoma
At Sheba Medical Center, children and young patients with primary central nervous system (CNS) lymphoma have access to one of the most advanced and specialized CAR-T therapy programs in the world. This rare and complex lymphoma, affecting the brain and spinal cord, requires highly precise and coordinated care, especially in relapsed or treatment-resistant cases.
A Personalized Treatment Designed for Each Patient
CAR-T therapy uses the patient’s own immune system to recognize and destroy cancer cells. For CNS lymphoma, this innovative approach offers a targeted option when conventional therapies are no longer sufficient.
At Sheba, the entire CAR-T process is performed on-site, ensuring speed, precision, and optimal cell quality:
Apheresis – collection of the patient’s T-cells
Cell Engineering – genetic modification at Sheba’s Advanced Biotherapy Center
Infusion – reintroduction of modified cells to target lymphoma cells
Because no steps are outsourced, treatment can begin quickly and is typically completed within ~10 days. CAR-T acts as a “living therapy,” continuing to work in the body and offering the potential for long-term disease control.
Expert Pediatric Leadership and Multidisciplinary Care
The program is led by Prof. Amos Toren, a globally recognized expert in pediatric hemato-oncology and cellular therapies, with decades of experience and over 1,500 bone marrow transplants performed.
Given the complexity of CNS lymphoma, care is delivered through a multidisciplinary team, including pediatric hemato-oncologists, neurologists, neurosurgeons, and radiology experts.
The program includes:
Specialized pediatric CAR-T units with 24/7 monitoring
Advanced neuro-imaging and precision diagnostics
A supportive, family-centered environment
Full international patient services, including travel and care coordination
Proven Expertise in Complex and High-Risk Cases
Sheba is a global leader in CAR-T therapy, with strong outcomes across hematologic cancers:
~90% remission in pediatric patients
~80% in young adults (up to 23 years)
~70% in adults
The team has extensive experience in treating rare and high-risk conditions, including CNS involvement, offering advanced options when other treatments are limited.
Comprehensive Evaluation and Ongoing Support
Each patient undergoes a full diagnostic work-up, including:
advanced brain and spinal imaging (MRI/CT), bone marrow evaluation, genetic and molecular testing, and cardiac and pulmonary assessment.
Care is provided in English, Russian, and Arabic, ensuring families feel supported and informed throughout the entire journey.
A Trusted Place for Advanced Pediatric Neuro-Oncology Care
By combining cutting-edge immunotherapy, neurological expertise, and compassionate care, Sheba provides one of the most advanced environments for treating primary CNS lymphoma with CAR-T focused on achieving the best possible outcomes and quality of life for every patient.
Assistenza Bookimed 24/7
- Coordinatore medico personale
- Organizzazione dei viaggi medici — prenotazione di biglietti aerei e camere d'albergo a prezzi speciali per i partner
- Tutela degli interessi dei pazienti durante il viaggio medico
Prezzo del programma
Cosa NON include questo pacchetto
Medico
Dr. Amos Toren is a pediatric hemato-oncologist at Sheba Medical Center. He served as Director of the Pediatric Hemato-Oncology and Bone Marrow Transplant Division. Dr. Toren holds a PhD in Human Genetics. He specializes in CAR T-cell therapy and bone marrow transplantation for children. Forbes Israel has recognized his expertise in hematology.
- Served as the Head of the Hematology Division at Tel Aviv University.
- Treats complex cases of leukemia, lymphoma, and rare pediatric cancers.
- Member of the American Society of Hematology and European Group for Blood and Marrow Transplantation.
- Collaborates on research with the NIH and St. Jude Children’s Research Hospital.
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Informazioni sulla clinica
Il Centro Medico Sheba è uno dei migliori ospedali in Israele e nel mondo. La rivista internazionale Newsweek ha classificato l'Ospedale Sheba tra i 10 migliori ospedali del mondo nel 2020. L'ospedale copre 1.990 specialità e oltre 1.500.000 pazienti da tutto il mondo visitano l'Ospedale Sheba per cure ogni anno.
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