Autologous Stem Cell Transplantation for Pediatric Wilms’ Tumor at Sheba Hospital

• Consulto con un oncologo
• Analisi biochimica del sangue
• Consulto con un pediatra
• Analisi estesa del sangue
• Diagnostica complessa del nefroblastoma
• Trapianto autologo di midollo osseo
• Trattamento complesso del nefroblastoma
• 3 pasti al giorno dal nutrizionista
• Servizi infermieristici 24 ore su 24
• Elettrocardiogramma (ECG)
• Esami del sangue
• Radiografia del torace
• Test anti-HIV
• Test Anti-HBC
• Test Anti-HCVAb
• Ecocardiografia
• Emocromo completo (CBC)
• Esame di biochimica del sangue
• PET/TC
• Consultazione con un oncologo
• Consultazione con un ematologo
• Consultazione con un immunologo
• Consultazione con un nefrologo
• Consultazione con un cardiologo
• Consultazione con un ematologo pediatrico
• Consultazione con un pediatra
• Consultazione con un oncoematologo
• Risonanza magnetica della testa
• Biopsia
• Mineralometria Computerizzata Ossea (MOC)
• Emocromo completo con marcatori tumorali e proteinogramma

• 30 giorni in ospedale

• Trasferimento aeroporto-clinica-aeroporto

Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation) for Pediatric Wilms’ Tumor at Sheba Hospital

Sheba Medical Center – Advanced, Personalized Transplant Care for Children

At Sheba Medical Center, we understand how overwhelming it can be for families to face a diagnosis of Wilms’ tumor. As one of the most common kidney cancers in children, it is often highly treatable, but in some cases, more advanced care is needed.

For children with high-risk, relapsed, or treatment-resistant Wilms’ tumor, Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation) is a part of a comprehensive treatment approach offering an additional option aimed at improving long-term outcomes.

Our pediatric transplant program combines world-class expertise, innovative therapies, and compassionate, family-centered care to support children and their families throughout every stage of treatment.

When is a Bone Marrow Transplant Needed?

Bone marrow transplantation is not routinely required for most children with Wilms’ tumor, but may be recommended in specific situations, including:

High-risk disease, particularly with spread beyond the kidney
Relapsed Wilms’ tumor, when the disease returns after initial treatment
Cases where a more intensive treatment strategy is needed

In these cases, BMT allows doctors to deliver high-dose chemotherapy to target cancer cells, followed by the infusion of healthy stem cells to restore bone marrow and support recovery.

Types of Transplant
Autologous Transplant (Child’s Own Cells)

This is the most commonly used transplant approach when BMT is part of treatment for Wilms’ tumor.

Stem cells are collected from the child before intensive therapy
High-dose chemotherapy is administered
The child’s own stem cells are reinfused to rebuild healthy bone marrow

This approach enables effective treatment while supporting safe recovery.

Advanced Pediatric Wilms’ Tumor Care

Treatment at Sheba is highly coordinated and tailored to each child:

Integration of chemotherapy, surgery, and radiotherapy with transplant strategies
Access to innovative and targeted therapies when appropriate
Close collaboration between pediatric oncologists, surgeons, and transplant specialists
Comprehensive supportive care throughout treatment
Specialized Pediatric Transplant Environment

Children undergoing BMT are treated in dedicated pediatric transplant units designed for safety, comfort, and healing:

Child-friendly, highly protected environments
Advanced infection prevention systems
Continuous care by experienced pediatric specialists

Every aspect of care is adapted to support children physically and emotionally.

Clinical Expertise

Sheba Medical Center is a leading center for pediatric oncology and transplantation, offering:

Experience in managing complex and high-risk Wilms’ tumor cases
Expertise in high-dose therapy with stem cell support
Outcomes aligned with leading international centers
Long-term follow-up focused on recovery, growth, and quality of life
Care That Supports the Whole Family

We understand that treating a child means caring for the entire family.

At Sheba, families are supported by a multidisciplinary team including physicians, nurses, psychologists, and care coordinators ensuring guidance, reassurance, and continuous support throughout the journey.

Why Families Choose Sheba for Pediatric BMT

Leading pediatric transplant center
Expertise in complex pediatric cancers
Access to a wide range of donor options
Advanced treatment technologies
Compassionate, child-centered care
Dedicated international patient services

A Message of Hope

At Sheba Medical Center, we combine advanced science with compassionate pediatric care. Even in more complex cases of Wilms’ tumor, our goal is to provide every child with the strongest possible chance for recovery, while supporting families with confidence, care, and hope every step of the way.

• Coordinatore medico personale
• Organizzazione dei viaggi medici — prenotazione di biglietti aerei e camere d'albergo a prezzi speciali per i partner
• Tutela degli interessi dei pazienti durante il viaggio medico