Autologous Stem Cell Transplantation for Pediatric Osteosarcoma at Sheba Hospital

• Consulto con un oncologo
• Trapianto autologo di midollo osseo
• 3 pasti al giorno dal nutrizionista
• Servizi infermieristici 24 ore su 24
• Elettrocardiogramma (ECG)
• Esami del sangue
• Radiografia del torace
• Test anti-HIV
• Test Anti-HBC
• Test Anti-HCVAb
• Ecocardiografia
• Emocromo completo (CBC)
• Esame di biochimica del sangue
• PET/TC
• Consultazione con un oncologo
• Consultazione con un ematologo
• Consultazione con un immunologo
• Consultazione con un cardiologo
• Consultazione con un ematologo pediatrico
• Consultazione con un pediatra
• Consultazione con un oncoematologo
• Risonanza magnetica della testa
• Biopsia
• Mineralometria Computerizzata Ossea (MOC)
• Emocromo completo con marcatori tumorali e proteinogramma

• 30 giorni in ospedale

• Trasferimento aeroporto-clinica-aeroporto

Autologous Stem Cell Transplantation for Pediatric Osteosarcoma
Sheba Medical Center – Advanced, Personalized Care for Children

At Sheba Medical Center, we understand how challenging it can be for families to face a diagnosis of osteosarcoma. As the most common primary bone cancer in children and adolescents, osteosarcoma requires highly specialized treatment and close collaboration between pediatric oncologists, orthopedic surgeons, and transplant specialists.

While many children achieve excellent outcomes with a combination of chemotherapy and surgery, some cases require a more intensive treatment approach. For selected children with advanced, metastatic, or relapsed osteosarcoma, high-dose chemotherapy supported by Autologous Stem Cell Transplantation (ASCT) may offer an additional therapeutic option.

At Sheba, we combine world-class expertise, innovative treatment strategies, and compassionate family-centered care to provide every child with the most advanced treatment opportunities available.

When is Autologous Stem Cell Transplantation Considered?

Autologous Stem Cell Transplantation is not routinely used for all children with osteosarcoma. However, it may be considered in carefully selected situations, including:

Metastatic osteosarcoma
Relapsed disease
High-risk cases requiring intensified treatment
Children participating in specialized treatment protocols

In these situations, high-dose chemotherapy may be used to target resistant cancer cells. Stem cell transplantation allows doctors to safely administer these intensive treatments while supporting the body's recovery afterward.

How the Treatment Works

Stem Cell Collection

Before treatment begins, healthy blood-forming stem cells are collected from the child's bloodstream and carefully preserved.

High-Dose Chemotherapy

The child receives intensive chemotherapy designed to target remaining osteosarcoma cells throughout the body.

Stem Cell Rescue

After chemotherapy, the child's previously collected stem cells are reinfused to restore bone marrow function and support the recovery of healthy blood cells and the immune system.

This process allows physicians to deliver highly intensive treatment while helping the body recover efficiently.

Advanced Pediatric Sarcoma Care

At Sheba Medical Center, every treatment plan is tailored to the individual child.

Our multidisciplinary team integrates:

Pediatric oncology expertise
Advanced orthopedic oncology surgery
High-dose chemotherapy protocols
Stem cell transplantation when appropriate
Innovative supportive care strategies

This coordinated approach ensures that every child receives comprehensive care designed around their specific needs.

Specialized Pediatric Transplant Environment

Children undergoing stem cell transplantation are treated in dedicated pediatric transplant units designed specifically for safety, comfort, and healing.

Care includes:

Child-friendly treatment environments
Advanced infection prevention systems
Continuous monitoring by experienced pediatric specialists
Comprehensive supportive care throughout treatment and recovery

Every aspect of care is focused on helping children and families feel supported throughout their journey.

Clinical Expertise

Sheba Medical Center is internationally recognized for pediatric cancer care and stem cell transplantation, offering:

Extensive experience in treating complex pediatric solid tumors
Expertise in high-dose chemotherapy with stem cell support
Advanced multidisciplinary sarcoma care
Access to innovative treatment approaches and clinical research
Long-term follow-up focused on recovery, growth, and quality of life

Care That Supports the Whole Family

We understand that cancer treatment affects the entire family.

At Sheba, families are supported by a multidisciplinary team including physicians, nurses, psychologists, social workers, rehabilitation specialists, and care coordinators. From diagnosis through recovery, we provide guidance, reassurance, and ongoing support every step of the way.

Why Families Choose Sheba

Leading pediatric oncology and transplant center
Expertise in advanced osteosarcoma treatment
Experience with high-dose chemotherapy and stem cell support
Multidisciplinary care from internationally recognized specialists
Child-centered, family-focused approach
Dedicated international patient services
A Message of Hope

At Sheba Medical Center, we believe every child deserves access to the most advanced therapies available. Through innovative treatment strategies, specialized expertise, and compassionate care, we are committed to helping children with osteosarcoma achieve the best possible outcomes while supporting families with confidence, strength, and hope throughout their journey.

• Coordinatore medico personale
• Organizzazione dei viaggi medici — prenotazione di biglietti aerei e camere d'albergo a prezzi speciali per i partner
• Tutela degli interessi dei pazienti durante il viaggio medico