Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation) for Pediatric Ewing Sarcoma at Sheba Hospital - a JCI accredited and Top-10 Hospitals 2026 by Newsweek

• PET/TC
• Consulto con un oncologo
• Esami di laboratorio
• Emocromo completo
• Biopsia
• Scintigrafia
• Analisi estesa del sangue
• Consultazione di un radiologo
• Diagnostica complessa del sarcoma di Ewing
• Trattamento complesso del sarcoma di Ewing
• 3 pasti al giorno dal nutrizionista
• Servizi infermieristici 24 ore su 24
• Elettrocardiogramma (ECG)
• Esami del sangue
• Radiografia del torace
• Test anti-HIV
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• Test Anti-HCVAb
• Ecocardiografia
• Emocromo completo (CBC)
• Esame di biochimica del sangue
• PET/TC
• Consultazione con un cardiologo
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• Consultazione con un oncoematologo
• Risonanza magnetica della testa
• Biopsia
• Mineralometria Computerizzata Ossea (MOC)
• Emocromo completo con marcatori tumorali e proteinogramma

• 30 giorni in ospedale

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Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation) for Pediatric Ewing Sarcoma

Sheba Medical Center – Advanced, Personalized Transplant Care for Children

At Sheba Medical Center, we understand how overwhelming it can be for families to face a diagnosis of Ewing Sarcoma. This rare and aggressive childhood cancer requires highly specialized care, precision treatment, and a deeply supportive environment for both the child and their family.

For children with high-risk, recurrent, or treatment-resistant Ewing Sarcoma, Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation) may be considered as part of an advanced treatment strategy, offering a powerful approach aimed at improving long-term outcomes.

Our pediatric transplant program combines world-class expertise, innovative therapies, and compassionate, family-centered care at every stage of the journey.

When is a Bone Marrow Transplant Needed?

Bone marrow transplantation is not part of standard treatment for all children with Ewing Sarcoma, but is recommended in specific situations, including:

High-risk disease, particularly with spread beyond the primary tumor
Relapsed Ewing Sarcoma, when the disease returns after initial treatment
Refractory disease, when standard therapies are not sufficient

In these cases, BMT allows the use of high-dose chemotherapy to target cancer cells, followed by the infusion of healthy stem cells to restore the bone marrow and immune system.

Types of Transplant

Autologous Transplant (Child’s Own Cells)

This is the most commonly used transplant approach in Ewing Sarcoma when BMT is indicated.

Stem cells are collected from the child in advance
Intensive therapy is administered to eliminate cancer cells
The child’s own stem cells are reinfused to support recovery

This approach enables the safe delivery of higher-intensity treatment.

Advanced Pediatric Sarcoma Care

Treatment for Ewing Sarcoma at Sheba is highly coordinated and personalized:

Integration of chemotherapy, surgery, and radiotherapy with transplant strategies
Access to innovative and targeted therapies when appropriate
Close collaboration between pediatric oncologists, orthopedic surgeons, and transplant specialists
Advanced supportive care throughout treatment
Specialized Pediatric Transplant Environment

Children undergoing transplantation are cared for in dedicated pediatric units designed to support healing and comfort:

Child-friendly, protected environments
Advanced infection prevention systems
Continuous monitoring by experienced pediatric teams

Every aspect of care is tailored to the needs of growing children.

Clinical Expertise

Sheba Medical Center is a leading center for pediatric oncology and transplantation, offering:

Experience in managing complex and high-risk Ewing Sarcoma cases
Expertise in high-dose therapy with stem cell support
Outcomes aligned with leading international centers
Long-term follow-up focused on recovery, growth, and quality of life
Care That Supports the Whole Family

We understand that treating a child means supporting the entire family.

At Sheba, families are guided by a multidisciplinary team including physicians, nurses, psychologists, and care coordinators ensuring clear communication, emotional support, and continuity of care throughout the journey.

Why Families Choose Sheba for Pediatric BMT

Leading pediatric transplant center
Expertise in rare and complex sarcomas
Access to a wide range of donor options
Advanced treatment technologies
Compassionate, child-centered care
Dedicated international patient services

A Message of Hope

At Sheba Medical Center, we combine advanced science with compassionate pediatric care. Even in complex conditions like Ewing Sarcoma, our goal is to provide every child with the strongest possible chance for recovery—while supporting families with confidence, care, and hope every step of the way.

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